Table 2.
Characteristics of ECMO-supported and non-ECMO-supported neonates with severe ARDS after propensity score matching.
| Characteristics | ECMO (n = 31) | Non-ECMO (n = 31) | P-value |
|---|---|---|---|
| BASIC INFORMATION | |||
| Age at admission (h), median (IQR) | 7 (5~14) | 5 (4~10) | 0.408 |
| GA (Weeks), median (IQR) | 39+3 (38+1~40+5) | 39+1 (38~40) | 0.607 |
| Body weight (g) | 3364.84 ± 472.05 | 3285.81 ± 560.69 | 0.551 |
| Sex, n (%) | 0.118 | ||
| Male | 22 (71.0%) | 16 (51.6%) | |
| Female | 9 (29.0%) | 15 (48.4%) | |
| Delivery, n (%) | 0.788 | ||
| Spontaneous labor | 11 (35.5%) | 10 (32.3%) | |
| Cesarean delivery | 20 (64.5%) | 21 (67.7%) | |
| Diagnoses, n (%) | 0.149 | ||
| MAS | 12 (38.7%) | 8 (25.8%) | |
| Sepsis | 6 (12.9%) | 2 (6.5%) | |
| Pneumonia | 8 (25.8%) | 16 (51.6%) | |
| Asphyxia | 5 (16.1%) | 5 (16.1%) | |
| ILLNESS SEVERITY METRICS PRE-ECMO | |||
| OI, median (IQR) | 46.3 (40.6~62.5) | 41 (35.2~62.5) | 0.147 |
| PH, median (IQR) | 7.24 (7.08~7.33) | 7.20 (7.12~7.33) | 0.959 |
| PaO2, median (IQR) | 36 (30~47) | 29 (22~32) | 0.019* |
| PaCO2, median (IQR) | 53.0 (39.7~59) | 45 (36~59) | 0.408 |
| BE, median (IQR) | −7.4 (−15.7~-2.5) | −6.6 (−9.5~-3.4) | 0.253 |
| Lactate, median (IQR) | 7.7 (4.4~13.2) | 2.6 (4.67~6.8) | 0.04* |
| Treatment PRE-ECMO | |||
| NO, n (%) | 20 (64.5%) | 13 (41.9%) | 0.075 |
| PS, n (%) | 26 (83.9%) | 27 (87.1%) | 1 |
| Ventilation, n (%) | 0.168 | ||
| HFOV | 19 (61.3%) | 24 (77.4%) | |
| CMV | 12 (38.7%) | 7 (22.6%) | |
ECMO, extracorporeal membrane oxygenation; IQR, interquartile range; GA, gestational age; MAS, meconium aspiration syndrome; OI: oxygenation index; BE, base excess; NO, nitric oxide; PS, pulmonary surfactant; HFOV, high frequency oscillatory ventilation; CMV, conventional mechanical ventilation;
*
defined as P < 0.05;
**
defined as P < 0.01.