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. 2019 Dec 13;19(1):13–27. doi: 10.1007/s40200-019-00469-0

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Fig. 6 — Effect of macrophage on the expression of miR-29b, HDAC4, IL-6, Caspase-3, and Fibronectin. a & b. Relative mRNA expression levels of IL-6, caspase-3 and fibronectin were increased in the co-culture of podocytes and macrophages under hyperglycaemic conditions as compared to the control group as per the real-time PCR analysis. c. Relative miR-29b expression levels were downregulated in the co-culture of podocytes and macrophages under hyperglycaemic conditions as compared to the control group when analyzed through real-time PCR. d. Relative mRNA expression levels of HDAC4 were increased in the co-culture of podocytes and macrophages under hyperglycaemic conditions as compared to the control group when analyzed through real-time PCR. Data are expressed as the mean ± SD calculated from three experiments. * depicts P < 0.05, ** depicts P < 0.01 and *** depicts P < 0.001 in comparison to the control group. HG, High glucose; IL-6, Interleukin-6 (n = 3)