Table 1.
Features of COVID-19 in pregnancy stratified against SARS and MERS
| Characteristics | COVID-19 | SARS | MERS |
|---|---|---|---|
| No. of cases | 55 | 17 | 12 |
| Age (y) | 23−40 | 27−44 | 31−39 |
| Gestational age at infection (wk) | All were in the third trimester except 2 women who were <28 wk gestation | 4-32 | 4-38 |
| Respiratory comorbidities (n) | None | Asthma (1) | Asthma (1), pulmonary fibrosis (1) |
| Symptoms | |||
| Fever (%) | 84b | 100 | 58 |
| Cough (%) | 28b | 76 | 67 |
| Dyspnea (%) | 18b | 35 | 58 |
| Investigationsa | |||
| CXR/CT evidence of pneumonia | 76b | 100b | 100b |
| Leukocytosis (%) | 38b | 40b | 50b |
| Lymphopenia (%) | 22b | 67b | 50b |
| Thrombocytopenia (%) | 13b | 36b | 50b |
| Maternal complications | |||
| Mortality (%) | 0 | 18 | 25 |
| Mechanical ventilation (%) | 2 | 35 | 41 |
| Fetal complications | |||
| Miscarriage/stillbirth (%) | 2 | 25c | 18b |
| IUGR (%) | 9 | 13c | 9b |
| Preterm birth (%) | 43 | 25c | 27b |
| Neonatal complications | |||
| Neonatal death (%) | 2 | 0c | 9b |
Data shown in the table are pooled from references18,35, 36, 37, 38, 39,75, 76, 77 (COVID-19);1,78, 79, 80, 81, 82(SARS);2,27,29,83, 84, 85, 86, 87 (MERS). COVID-19, coronavirus disease 2019; CT, computed tomography; CXR, chest X-ray; IUGR, intrauterine growth restriction; MERS, Middle East respiratory syndrome; SARS, severe acute respiratory syndrome.
Dashraath. COVID-19 pandemic and pregnancy. Am J Obstet Gynecol 2020.
CXR/CT evidence of pneumonia included ground-glass opacities, focal or bilateral patchy shadowing, and interstitial abnormalities. Leukocytosis was defined as a white blood cell count of >11,000/mm3. Lymphopenia was defined as a lymphocyte count of <1000/mm3. Thrombocytopenia was defined as a platelet count of <150,000/mm3
Patients whose data were not reported were excluded from the calculations
One patient who aborted her pregnancy was excluded from the calculations.