Table 2.
Leave-one-out sensitivity analyses for tight versus standard blood pressure targets in Asian patients with hypertension.
| Study name, year | Tight versus standard SBP targets irrespective of age: HR (95% CI) | Tight versus standard DBP targets irrespective of age: HR (95% CI) | Tight versus standard DBP targets in middle-aged patients: HR (95% CI) | ||
|---|---|---|---|---|---|
| MACCEs | Stroke | MACCEs | Stroke | MACCEs | |
| Fan 201726 | 0.82 (0.71, 0.96) | 0.87 (0.77, 0.98) | 0.86 (0.77, 0.97) | 0.84 (0.73, 0.96) | - |
| Kamishima 201928 | 0.79 (0.68, 0.93) | - | - | - | - |
| Kario 201429 | 0.77 (0.67, 0.89) | - | - | - | - |
| Lee 201730 | 0.78 (0.67, 0.90) | 0.78 (0.66, 0.92) | 0.86 (0.77, 0.97) | 0.66 (0.45, 0.95) | - |
| Lee 201831 | 0.80 (0.66, 0.98) | 0.76 (0.61, 0.94) | 0.86 (0.77, 0.97) | 0.65 (0.46, 0.92) | 0.80 (0.69, 0.93) |
| Ogihara 200932,33 | 0.80 (0.69, 0.93) | - | 0.78 (0.66, 0.92) | - | 0.78 (0.74, 0.81) |
| Teramoto 201235 | 0.79 (0.68, 0.92) | 0.82 (0.71, 0.95) | 0.75 (0.63, 0.90) | 0.71 (0.54, 0.93) | - |
| Wan 201836 | 0.78 (0.65, 0.93) | 0.76 (0.63, 0.91) | - | - | 0.77 (0.74, 0.81) |
| Yamashita 201338 | 0.80 (0.69, 0.93) | - | 0.77 (0.65, 0.91) | - | - |
| Yamazaki 201339 | 0.79 (0.67, 0.92) | 0.82 (0.70, 0.95) | 0.77 (0.64, 0.92) | 0.73 (0.56, 0.96) | 0.78 (0.74, 0.81) |
| Zheng 201540 | 0.87 (0.77, 0.98) | 0.86 (0.77, 0.97) | - | - | - |
MACCEs: major adverse cardiac and cerebrovascular events.