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. 2020 May 1;13(5):1190–1196.

Table 1.

Clinical characteristics of lung carcinomas spontaneous regression

Ref. Age Sex Metastasis Regression TNM Pathologic examination Pathologic diagnosis Associated treatments or health conditions Follow-up (month)
1 Cafferata, MA [14] 68 M None Complete regression Stage I CT-guided fine needle aspiration biopsy Poorly differentiated pulmonary adenocarcinoma Unknown 48
2 Pujol, JL [34] 75 F N/A Complete regression N/A Fine-needle transbronchial biopsy Non-small cell lung cancer Anti-Hu Antibody Syndrome 18
3 Gladwish, A [35] 81 F Lymph node metastases Partial regression T2N3M0 Ultrasound-guided biopsy Moderately differentiated squamous cell carcinoma Essiac tea 18
4 Menon, MP [26] 44 M Brain and adrenal gl and metastases Partial regression N/A Biopsies of both the adrenal gland and lung Poorly differentiated non-small-cell carcinoma HAART (AIDS) 60
5 Lee, YS [20] 70 F N/A Complete regression N/A Bronchoscopy biopsy Small cell lung cancer (SCLC) Lower respiratory tract infection (fever and cough with yellowish sputum) 132
6 Choi, SM [24] 71 M N/A Complete regression N/A Bronchoscopy biopsy Squamous cell carcinoma Pulmonary tuberculosis 10
7 Nakamura, Y [29] 71 M None Complete regression cT4N0M0 Thoracoscopy Poorly differentiated adenocarcinoma Anti-NY-ESO-1 immunity 5
8 Mawhinney, E [36] N/A F N/A Complete regression N/A Bronchoscopy Atypical cells suggestive of SCLC Ataxic sensorimotor neuropathy with mild weakness (intravenous immunoglobulin and intravenous methylprednisolone and subsequent oral corticosteroid) 18 DEATH for Neurologic disorder
9 Asada, M [37] 88 M N/A Complete regression N/A Sputum cytology Squamous cell carcinoma Tiapride for the treatment of senile mental illness 4
10 Haruki, T [31] 69 F Partial regression cT1N2M1 CT-guided needle biopsy Lung adenocarcinoma Immunological CD8+ T cell 14
11 Darnell, RB [38] 60 M N/A Complete regression N/A Biopsy specimen Small cell lung cancer (SCLC) Paraneoplastic neuronal antibodies 72
12 Darnell, RB [38] 71 M None Complete regression N/A N/A N/A Hu-antibody positive 12 and Death for Her neurological state progressively deteriorated
13 Nakano, T [25] 50 F Lymph node metastases Complete regression N/A Bronchoscopy examination Small cell lung carcinoma (SCLC) hepatitis B cell strain 72 months and died for hepatocellular carcinoma
14 Sperduto, P [39] 61 M Adrenal metastasis Complete regression N/A Needle aspiration Squamous cell carcinoma auditory hallucinations (treated with amitriptyline and perphenazine) 24