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. 2020 May 1;13(5):1176–1184.

Table 2.

Associations between expression of Nanog, CD133, and WWOX and clinicopathologic characteristics of invasive breast carcinoma (IBC)

Variable Nanog P CD133 P WWOX P



- + - + - +
Age (years) 0.876 0.592 0.619
    < 50 54 80 53 81 70 64
    ≥ 50 29 41 25 45 34 36
Location 0.477 0.537 0.885
    Left 46 57 40 63 52 51
    Right 34 60 34 60 49 45
    Bilateral 3 4 4 3 3 4
Smoking 0.483 0.122 0.168
    No 71 99 69 101 83 87
    Yes 12 22 9 25 21 13
Size (cm) < 0.001 0.014 0.002
    ≤ 2.0 38 21 31 28 23 36
    2.0 < S ≤ 5.0 43 79 42 80 62 60
    > 5.0 2 21 5 18 19 4
Differentiation < 0.001 < 0.001 < 0.001
    G 1 39 11 34 16 13 37
    G 2 37 61 38 60 52 46
    G 3 7 49 6 50 39 17
Tumor stage < 0.001 0.046 0.005
    T1 39 21 31 29 22 38
    T2 40 77 41 76 61 56
    T3 2 16 4 14 14 4
    T4a 2 7 2 7 7 2
LNM 0.001 < 0.001 < 0.001
    N0 57 49 55 51 34 72
    N1 20 49 21 48 45 24
    N2 6 18 1 23 20 4
    N3 0 5 1 4 5 0
TNM stages < 0.001 < 0.001 < 0.001
    I 26 7 24 9 7 26
    II 48 78 49 77 60 66
    III 9 36 5 40 37 8
ER expression 0.074 0.255 0.011
    Negative 32 62 32 62 57 37
    Positive 51 59 46 64 47 63
PR expression 0.011 0.085 0.026
    Negative 40 80 40 80 69 51
    Positive 43 41 38 46 35 49
HER2 expression 0.002 0.002 < 0.001
    Negative 69 76 65 80 57 88
    Positive 14 45 13 46 47 12