Table 3.
Distribution of Etiologic Microorganisms in Patients With Pyogenic Vertebral Osteomyelitis According to Comorbidities
| Patients With DM (n = 180) | Patients Without DM (n = 406) | P | Patients With LC (n = 55) | Patients Without LC (n = 531) | P | Patients With CRD (n = 61) | Patients Without CRD (n = 525) | P | Patients With Solid Tumor (n = 84) | Patients Without Solid Tumor (n = 502) | P | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Staphylococcus aureus | 84 (46.7) | 171 (42.1) | .306 | 14 (25.5) | 241 (45.4) | .005 | 32 (52.5) | 223 (42.5) | .14 | 27 (32.1) | 228 (45.4) | .023 |
| MSSA | 49 (27.2) | 108 (26.6) | .876 | 10 (18.2) | 147 (27.7) | .130 | 11 (18.0) | 146 (27.8) | .103 | 14 (16.7) | 143 (28.5) | .024 |
| MRSA | 35 (19.4) | 63 (15.5) | .240 | 4 (7.3) | 94 (17.7) | .048 | 21 (34.4) | 77 (14.7) | <.001 | 13 (15.5) | 85 (16.9) | .741 |
| MSCNS | 3 (1.7) | 9 (2.2) | .764 | 1 (1.8) | 11 (2.1) | 1.000 | 1 (1.6) | 11 (2.1) | >.99 | 3 (3.6) | 9 (1.8) | .394 |
| MRCNS | 5 (2.8) | 14 (3.4) | .672 | 2 (3.6) | 17 (3.2) | .696 | 1 (1.6) | 18 (3.4) | .709 | 1 (1.2) | 18 (3.6) | .500 |
| Enterococcus species | 10 (5.6) | 12 (3.0) | .127 | 0 (0) | 22 (4.1) | .252 | 5 (8.2) | 17 (3.2) | .068 | 1 (1.2) | 21 (4.2) | .346 |
| Streptococcus species | 34 (18.9) | 84 (20.7) | .616 | 16 (29.1) | 102 (19.2) | .082 | 10 (16.4) | 108 (20.6) | .441 | 23 (27.4) | 95 (18.9) | .074 |
| Gram-negative bacilli | 37 (20.6) | 93 (22.9) | .527 | 18 (32.7) | 112 (21.1) | .048 | 10 (16.4) | 120 (22.9) | .250 | 26 (31.0) | 104 (20.7) | .037 |
| Anaerobes | 3 (1.7) | 8 (2.0) | 1.000 | 3 (5.5) | 8 (1.5) | .075 | 0 (0) | 11 (2.1) | .615 | 0 (0) | 11 (2.2) | .379 |
| Polymicrobial | 2 (1.1) | 7 (1.7) | .729 | 1 (1.8) | 8 (1.5) | .591 | 2 (3.3) | 7 (1.3) | .239 | 2 (2.4) | 7 (1.4) | .624 |
| Other | 2 (1.1) | 8 (2.0) | .731 | 0 (0) | 10 (1.9) | .610 | 0 (0) | 10 (1.9) | .610 | 1 (1.2) | 9 (1.8) | >.99 |
Data are presented as No. (%) of patients unless otherwise indicated.
Abbreviations: CRD, chronic renal disease; DM, diabetes mellitus; LC, liver cirrhosis; MRCNS, methicillin-resistant coagulase-negative; MRSA, methicillin-resistant Staphylococcus aureus; MSCNS, methicillin-sensitive coagulase-negative Staphylococcus; MSSA, methicillin-sensitive Staphylococcus aureus.
aActive localized or metastatic solid tumor.