Table 1. Demographics, Clinical Presentation, and Comorbidities in Nonsevere and Severe Disease.
| Characteristic | No. (%) | P value | |
|---|---|---|---|
| Nonsevere (n = 41) | Severe (n = 9) | ||
| Male sex | 23 (56) | 4 (44) | .71 |
| White | 22 (54) | 5 (56) | >.99 |
| Hispanic | 21 (51) | 4 (44) | >.99 |
| Age, median (range) | 9 y (6 d-21 y) | 14 y (8 y-19 y) | <.001 |
| Infants younger than 1 y | 14 (34) | 0 | .05 |
| Signs or symptoms at time of admission | |||
| Fever | 31 (76) | 9 (100) | .17 |
| Cough | 17 (41) | 6 (67) | .27 |
| Shortness of breath/dyspnea | 9 (22) | 8 (89) | <.001 |
| Chest pain | 6 (15) | 3 (33) | .33 |
| Gastrointestinal tract symptomsa | 3 (7) | 4 (44) | .01 |
| Sore throat | 4 (10) | 2 (22) | .29 |
| Congestion/runny nose | 3 (7) | 3 (33) | .06 |
| Comorbidities | |||
| Any | 25 (61) | 8 (89) | .14 |
| Obesityb | 5 (20) | 6 (67) | .03 |
| Asthma | 4 (10) | 2 (22) | .29 |
| Immunosuppressionc | 7 (17) | 1 (11) | .66 |
| Neurologicd | 6 (15) | 1 (11) | >.99 |
| Sickle cell disease | 1 (2) | 1 (11) | .33 |
| Cardiac diseasee | 3 (7) | 1 (11) | .56 |
| Diabetes | 1 (2) | 2 (22) | .79 |
| Genetic syndromes | 3 (7) | 2 (22) | .22 |
| Chronic respiratory diseasef | 2 (5) | 0 | >.99 |
a
Gastrointestinal tract symptoms included abdominal pain (5 [10%]), vomiting (3 [6%]), and diarrhea (2 [4%]).
b
Denominator for this row only includes patients 2 years and older (25 nonsevere [50%] and 9 severe [18%]).
c
Immunosuppressed patients included solid organ transplant recipients (2 [4%]), those with hematologic malignancy (2[4%]), those with solid tumors (2 [4%]), hematopoietic stem cell transplant recipients (1 [2%]), and those with aplastic anemia (1 [2%]).
d
Neurologic conditions included seizure disorder, neurodegenerative disorders, and cerebral palsy.
e
Cardiac disease includes restrictive cardiomyopathy and congenital heart disease.
f
Includes bronchiolitis obliterans.