Figure 1.

Staining for IgA in kidney biopsy samples with IgA nephropathy and infection-associated glomerulonephritis. (a−c) Kidney biopsy sample from a patient with primary IgA nephropathy. (a) Globally sclerosed glomeruli were seen in the sections of frozen tissue submitted for immunofluorescence (hematoxylin-eosin stain). (b) Positive staining for IgA was seen in the sclerotic glomerulus and (c) glomeruli with open capillary loops (immunofluorescence). (d,e) Kidney biopsy sample from a patient with primary Staphylococcal infection−associated glomerulonephritis. (d) Globally sclerosed glomeruli were seen in the sections of frozen tissue submitted for immunofluorescence (hematoxylin-eosin stain). (e) Positive staining for IgA was not seen in the sclerotic glomerulus but was strongly positive in (f) glomeruli with open capillary loops (immunofluorescence). Original magnification ×200 for a, b, d, and e and ×400 for c and f.