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Chrysophanol causes cell death in the HNSCC cell lines FaDu and SAS. (a and b) After the incubation time course, cell viability was determined by using the MTT assay. (c) Morphological changes in cells were observed at the indicated concentrations. Bar = 100 μm. All data are presented as mean ± SEM, n = 3. ∗p < 0.05. ∗∗p < 0.01 compared with control (0 μm).
