Table 1.

Characteristics of the included studies.

Cancer	First author	Year	Country	Sample type	Sample size(n)	Detection method	Cut-off value	PT	Survival analysis	Multivariate analysis	Hazard ratios	NOS score
GC	Wei Zhang9	2018	China	Tissue	76	qRT-PCR	NA	no	OS	No	K-M curve	7
GC	Yufeng Wang16	2018	China	Tissue	64	qRT-PCR	NA	NA	OS, DFS	No	K-M curve	6
GC	Jianjun Peng17	2018	China	Tissue	58	qRT-PCR	mean	no	OS	Yes	K-M curve	6
GC	Zhi Ding18	2018	China	Tissue	72	qRT-PCR	median	no	OS	no	K-M curve	6
Breast cancer	Qiongyan Zou19	2017	China	Tissue	86	qRT-PCR	median	NA	NA	No	NA	8
Breast cancer	Jia Yao13	2017	China	Tissue	36	qRT-PCR	2-fold	NA	OS	Yes	Text	7
Ovarian cancer	Xiaoqian Wang20	2018	China	Tissue	60	qRT-PCR	median	NA	NA	No	NA	8
Ovarian cancer	Xiuyun Li34	2018	China	Tissue	62	qRT-PCR	mean	no	OS	Yes	K-M curve	6
Osteosarcoma	Xi Chen35	2018	China	Tissue	132	qRT-PCR	NA	no	OS	Yes	Text	7
Osteosarcoma	Guangling Yang12	2018	China	Tissue	46	qRT-PCR	mean	no	OS	No	K-M curve	8
Brain glioma	Rong Zhang23	2017	China	Tissue	47	qRT-PCR	median	NA	OS	Yes	Text	7
HCC	Shaling Li11	2017	China	Tissue	84	qRT-PCR	median	NA	OS	no	K-M curve	8
Pancreatic cancer	Xianping Cui24	2019	China	Tissue	77	qRT-PCR	NA	NA	OS	No	K-M curve	7
LAD	Chunfeng Liu25	2019	China	Tissue	80	qRT-PCR	median	no	OS	Yes	K-M curve	7
NSCLC	Lin Zhang19	2018	China	Tissue	45	qRT-PCR	median	NA	OS	No	K-M curve	7
Bladder cancer	Zhiyong Tuo10	2018	China	Tissue	128	qRT-PCR	median	no	OS, PFS	No	K-M curve	7
ccRCC	Guanghua Liu26	2018	China	Tissue	40	qRT-PCR	median	no	OS, DFS	No	K-M curve	8
CCA	Yue Yao13	2018	China	Tissue	75	qRT-PCR	mean	no	NA	No	NA	8
CRC	Zeming Jia27	2019	China	Tissue	61	qRT-PCR	NA	no	NA	No	NA	7

Abbreviations: GC, gastric cancer; HCC, hepatocellular carcinoma; LAD, lung adenocarcinoma; NSCLC, non-small cell lung cancer; ccRCC, clear cell renal cell carcinoma; CCA, cholangiocarcinoma; CRC, colorectal cancer; PT, preoperative treatment; NA, Not available.