Figure 8.

HB treatment enhanced TGF-β1 expression, decreased MMP9 production, and facilitated collagen growth. (a) immunofluorescence staining of TGF-β1 (red) and its quantitative results (n = 3 − 5 animals per group); scale bar: 200 μm, nucleus (blue); (b) MMP9 level (n = 6); (c) New collagen growth observed by using two-photon microscope at days 6 and 13 after wound surgery. The green indicated the background, and the purple indicated the new collagen tissue at the front of the wound healing. The data were expressed as mean ± SD, and significance was expressed as ^#P < 0.05 vs Con and ^∗P < 0.05 vs STZ.