Table 1.
Group | Vaccine formulations | No. of immunizations | Inoculum strainc | No. of buffaloes without clinical sign/total (%) |
---|---|---|---|---|
1 | 100 µg each rOmpH + CpG ODN 10 µga | 6 | M-1404 | 4/6 (66.67) |
2 | 200 µg each rOmpH + CpG ODN 10 µga | 6 | 6/6 (100) | |
3 | Commercial haemorrhagic septicemia vaccineb | 6 | 5/6 (83.33) | |
4 | No vaccination | 6 | 0/6 (0)d |
aIntranasal administration with 1.0 ml/dose. bIntramuscular administration with 1.0 ml/dose. cChallenge inoculum was 1 ml of PBS containing approximately 103 CFU/ml. dThis group was terminated due to the clinical signs of buffaloes.