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. 2020 Apr 19;21(6):e49054. doi: 10.15252/embr.201949054

Figure 7. Models of TF involvement in the post‐translational secretory pathway.

Figure 7

  1. Cartoon of the contribution of TF in cytoplasmic protein folding (left) and secretory protein targeting (right, black arrows). The secretory targeting factors SecB and SecA that act independently (grey arrows) or interface with TF are also shown. Blue, cyan: other folding chaperones.
  2. Schematic model of TF:pro‐OmpA targeted to the translocase with or without contributions from SecB and subsequent SecA C‐tail/SecB‐mediated control of pro‐OmpA translocation. Oval to rectangle transition in SecA signifies conformational changes. B: SecB; cyto: cytoplasm; IM: inner membrane; peri: periplasm.