Fig. 4.

Effect of miR-210 on the proliferation of HUVECs under high-glucose condition. a Cell transfection efficiency in HUVECs and miR-210 expression was upregulated by the miR-210 mimic and was downregulated by the miR-210 inhibitor. b Regulatory effect of miR-210 on cell proliferation. High glucose led to inhibited HUVEC proliferation, and this effect was ameliorated by the overexpression of miR-210, while it was aggravated by the knockdown of miR-210. LG low glucose (5 mM), HG high glucose (30 mM); *P < 0.05 compared to LG; ^#P < 0.05 compared to HG. Multiple comparisons were made using ANOVA followed by Tukey’s test