Table 1.
Baseline characteristics of the two study populations < 40 years of age
| The HITTS study (n = 16) | The TEX study (n = 12) | |||
|---|---|---|---|---|
| HIT group (n = 6) Mean ± SD or median (IR) |
MICT group (n = 10) Mean ± SD or median (IR) |
HIT group (n = 8) Mean ± SD or median (IR) |
Control group (n = 4) Mean ± SD or median (IR) |
|
| Age (years) | ||||
| Range 18–39 in both studies | 29.1 ± 7.6 | 27.8 ± 6.2 | 27.1 ± 7.6 | 28.0 ± 7.8 |
| Gender (count) | Women: 0, Men:6 | Women:5, Men:5 | Women: 3, Men: 5 | Women: 2, Men: 2 |
| Time after heart transplant at inclusion | 11 ± 2.7 (weeks) | 11 ± 1.5 (weeks) | 4.4 ± 3.3 (years) | 3.0 ± 0.0 (years) |
| Waitinglist (days) | 70 (160) | 62 (138) | ||
| Donor age (years) | 31 (35) | 31 (23) | 33 (17) | 38 (29) |
| Ischemic time (min) | 209 (206) | 214 (112) | 225 (45) † | 70 (95) † |
| Creatinine (μmol/l) | 115 (35) | 105 (60) | 91 (28) † | 77 (16) † |
| Primary diagnosis (count) | ||||
| Cardiomyopathy | 3 | 9 | 7 | 3 |
| Coronary artery disease | 1 | 0 | 0 | 0 |
| Other | 2 | 1 | 1 | 1 |
† p-value < 0.05 between groups at baseline (Mann-Whitney U -test). There were no other baseline differences between the exercise-groups
SD Standard deviation, IR Interquartile range, HIT High-intensity interval training, MICT Moderate intensity continuous training, HITTS High-intensity Interval Training in de novo heart Transplant recipients in Scandinavia, TEX Transplant EXercise