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. 2020 Apr 21;21(6):e50162. doi: 10.15252/embr.202050162

Figure EV1. Type I IFN signaling is retained in dormant PCa cells in bone metastases.

Figure EV1

  1. Consensus matrix of non‐negative matrix factorization analysis of all DEGs expressed between dormant and proliferating cells defines two dominant dormant (C1, C2) and one chiefly proliferating (C3) clusters (k = 3; Coph = 0.9995).
  2. Distribution of all genes contributing to each of the dominant three cluster metagenes (C1–3).
  3. goana gene ontology (GO) analysis (limma) showing the top 10 biological processes for all genes contributing to C1, C2, and C3 in order of fold enrichment. Gene sets appear in order of significance (P‐value) with color representing fold enrichment (FE) and bar width indicating the number of genes in each process.