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. 2020 Apr 14;21(6):e49273. doi: 10.15252/embr.201949273

Figure 7. PDS5 proteins affect meiotic recombination.

Figure 7

  • A–H
    Double immunolabeling of SYCP3 (red) and either γH2AX (pseudocolored in blue, A–D) or RAD51 (green, E–H) in Pds5AB cKO spread spermatocytes at the indicated stages.
  • I
    Scatter dot‐plot graph of the quantification of RAD51 foci in 15 zygotene nuclei randomly selected from three different individuals of each genotype. Bars indicate mean and standard error, and statistical significance was assessed with an unpaired two‐tailed t‐test function (****P < 0.0001).
  • J–L
    Double immunolabeling of MLH1 (pseudocolored in white) and SYCP3 (red) in Pds5AB cKO spread spermatocytes.
Data information: Sex bivalents (XY) are indicated. Scale bar, 10 μm.