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Flow of participants showing eligibility, recruitment, protocol deviations, withdrawals, and loss to follow-up in the REVAKI-2 trial. CKD, chronic kidney disease; CYP3A4, cytochrome P450 3A4; eGFR, estimated glomerular filtration rate; NAION, non-arteritic anterior ischaemic optic neuropathy; RRT, renal replacement therapy.
