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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Dev Dyn. 2019 Jun 19;248(9):762–770. doi: 10.1002/dvdy.66

FIGURE 2.

FIGURE 2

Drosophila ADCK1 mutants are larval lethal. A, The structure of the ADCK1 locus is depicted along with the locations of the two deletion alleles. The deleted regions are replaced with an eye-specific DsRed reporter in both mutants. B,C, Transheterozygotes of ADCK1/2 mutants display second instar larval lethality with double mouth hooks, indicative of a molting defect. The first and second instar mouth hooks are labeled. Scale bar: 20 μm. D,E, ADCK1/2 mutants display defects in tracheal morphology and tracheal breaks. Controls and mutants are depicted with representative images of the dorsal tracheal trunks. Panel E has an enlarged inset on the right. Scale bars: 0.25 mm (control), 0.2 mm (mutant)