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. 2020 Apr 15;20(1):335–342. doi: 10.3892/etm.2020.8668

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Copyright: © Tang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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GA decreases mitophagy/autophagy, exhibiting protective effects against H/R. (A) Following H/R induction, LC3B-I/II and p62 protein expression levels were detected by western blotting. ^*P<0.05 vs. normoxia group; ^#P<0.05 vs. the H/R+mock group. The (B) Cell Counting Kit-8 and (C) apoptosis assays were performed to assess cell viability following H/R induction. ^*P<0.05 vs. the H/R+mock group. GA, glycyrrhizic acid; H/R, hypoxia/reoxygenation; LC3B, microtubule associated protein 1 light chain 3B; NAC, N-acetylcysteine; OD, optical density; Rapa, rapamycin.