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. Author manuscript; available in PMC: 2020 Jun 4.
Published in final edited form as: Dev Cell. 2018 Aug 9;46(5):564–580.e5. doi: 10.1016/j.devcel.2018.07.010

Figure 4.

Figure 4.

Wnt activity in the developing OE coincides with Fgf20 expression

(A-E) Tcf/Lef:H2b-Gfp expression at E10.5 (A), E12.5 (B), E14.5 (C), E17.5 (D), and P7 (E). Arrowhead indicates rim of the nasal pit (NP). Arrow indicates epithelium outside of the nasal pit. * indicates site of future c1 development. RE, respiratory epithelium.

(D’) Magnification of boxed region in (D). Arrowheads indicate immature, negatively-curved OE.

(F,G) Tcf/Lef:H2b-Gfp and Fgf20βgal expression in Tcf/Lef:H2b-Gfp; Fgf20βgal/+ mice at E17.5.

Dashed line, epithelial-mesenchymal boundary. DAPI, nuclei. Scale bar, 100 μm (A-C), 500 μm (D-G, D’).