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. Author manuscript; available in PMC: 2020 Jun 4.
Published in final edited form as: Cell Rep. 2020 May 5;31(5):107605. doi: 10.1016/j.celrep.2020.107605

Figure 3. Homo- and Heterodimerization Propensities of mGluR2 with Other mGluR Subtypes.

Figure 3.

(A) Schematic showing group-I, -II, and -III mGluR subtypes tested in the LBD complementation assay.

(B) Cell images showing SNAP-mGluR2-LBD labeled with Alexa647 when co-expressed with mGluR3-GFP, mGluR4-GFP, or mGluR7-GFP (from left to right). All images are shown on the same fluorescence intensity scale. Scale bar, 10 µm.

(C) Quantification of Alexa647 fluorescence intensity when SNAP-mGluR2-LBD is co-expressed with other mGluR subtypes. Intensity values are normalized to the mGluR2/2 homodimerization condition and data are represented as mean ± SEM.

(D) Schematics showing the relative homo- and heterodimerization propensities of mGluR2.