Fig. 5. FGF9 and FGF10 have distinct effects on pseudoglandular stage lung epithelium.
(A) Anterior views of whole E12.5 lungs from mice expressing control (Sftpc-rtTA), FGF10 overexpression (SPC-FGF10-OE), or FGF9 overexpression (SPC-FGF9-OE) transgenes. All embryos were induced with doxycycline from E10.5–12.5. (B) Immunofluorescence showing SOX2 and SOX9 distribution. (C) Immunostaining showing SFTPC distribution. All images are representative of at least 3 embryos. Scale bars, 200 μm (A), 100 μm (B), 50 μm (C).