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. 2020 Jun 1;8:e9261. doi: 10.7717/peerj.9261

Table 1. Correlation of the PI3K/AKT/mTOR mRNA expression with OS in ccRCC patients (K-M plotter, n = 530).

Protein Gene HR (95% CI) P- value
PTEN PTEN 0.56 (0.41–0.75) <0.001
PI3K PIK3CA 0.52 (0.38–0.70) <0.001
PIK3CB 0.50 (0.37–0.68) <0.001
PIK3CD 1.38 (1.01–1.91) 0.046
PIK3CG 0.64 (0.47–0.87) 0.004
AKT AKT1 0.76 (0.56–1.02) 0.068
AKT2 1.34 (0.99–1.82) 0.055
AKT3 0.44 (0.32–0.62) <0.001
mTOR mTOR 0.54 (0.38–0.78) <0.001