Table 1. Correlation of the PI3K/AKT/mTOR mRNA expression with OS in ccRCC patients (K-M plotter, n = 530).
| Protein | Gene | HR (95% CI) | P- value |
|---|---|---|---|
| PTEN | PTEN | 0.56 (0.41–0.75) | <0.001 |
| PI3K | PIK3CA | 0.52 (0.38–0.70) | <0.001 |
| PIK3CB | 0.50 (0.37–0.68) | <0.001 | |
| PIK3CD | 1.38 (1.01–1.91) | 0.046 | |
| PIK3CG | 0.64 (0.47–0.87) | 0.004 | |
| AKT | AKT1 | 0.76 (0.56–1.02) | 0.068 |
| AKT2 | 1.34 (0.99–1.82) | 0.055 | |
| AKT3 | 0.44 (0.32–0.62) | <0.001 | |
| mTOR | mTOR | 0.54 (0.38–0.78) | <0.001 |