Table 2. Subgroup analysis of KRAS mutation status and the prognosis of CRC patients.
Group | Patients amount | KRAS MT vs. KRAS WT |
---|---|---|
Multivariate SH model | ||
HR (95% CI) | ||
All | 8,983 | 1.10 [1.04–1.17] |
Stage I | 586 | 1.30 [0.62–2.70] |
Stage II | 1,278 | 1.27 [0.95–1.69] |
Stage III | 2,381 | 1.28 [1.09–1.49] |
Stage IV | 4,635 | 1.14 [1.06–1.23] |
Unknown location | 257 | 1.01 [0.69–1.49] |
Left | 3,476 | 1.28 [1.15–1.42] |
Right | 3,593 | 1.07 [0.97–1.19] |
Rectum | 1,657 | 1.23 [1.07–1.43] |
Note:
KRAS MT, KRAS mutant; KRAS WT, KRAS wild type; HR, Hazard ratios; 95% CI, 95% confidence intervals; the significant results were bolded.