Table 4.
Exercise Capacity of Heart Failure with Preserved Ejection Fraction Patients with and without Anemia
| Exercise Parameter | Anemia | (n=76) | Without Anemia | (n=139) | p-value |
|---|---|---|---|---|---|
| 6-minute walk distance (m), median, (IQR) | 303.5 (193.5, 355.5) | 76 | 317.0 (241.0, 396.0) | 139 | 0.03 |
| Chronotropic incompetence (%) | 80% | 75 | 76% | 137 | 0.50 |
| Chronotropic index, median, (IQR) | 0.42 (0.25,0.62) | 75 | 0.52 (0.31,0.68) | 137 | 0.08 |
| Exercise Duration (min), median, (IQR) | 9.2 (7.3, 10.9) | 68 | 9.9 (7.8, 11.6) | 135 | 0.03 |
| Peak heart rate (beats/min), median, (IQR) | 104 (86, 122) | 75 | 111 (93, 128) | 137 | 0.02 |
| Peak systolic blood pressure (mmHg), median, (IQR) | 158 (132, 170) | 74 | 149 (130, 170) | 134 | 0.36 |
| Peak VO2 (ml/kg/min), median, (IQR) | 11.3 (9.6, 13.2) | 75 | 12.1 (10.7, 15.5) | 139 | 0.003 |
| Peak VO2 at VAT (ml/min) | 673.0 (544.0, 817.0) | 74 | 730.5 (550.0, 919.0) | 138 | 0.02 |
| Predicted 6-minute walk distance (% achieved), median, (IQR) | 65.0 (45.9, 77.2) | 76 | 72.1 (54.3, 84.7) | 139 | 0.01 |
| Predicted peak VO2 (% achieved), median, (IQR) | 38.6 (32.9, 44.6) | 75 | 42.6 (36.5, 51.3) | 139 | 0.001 |
| Respiratory exchange ratio, median, (IQR) | 1.11 (1.04, 1.19) | 75 | 1.07 (1.02, 1.15) | 139 | 0.007 |
Abbreviations: VO2=oxygen consumption; VAT=ventilatory anaerobic threshold; m=meters Chronotropic index = [peak HR — rest HR] / [(220-age) — rest HR].
Note: Data are presented as median (25th–75th percentile) or %.