Table 3.
Lactoferrin sources as supplements, and examples where it has been used to treat various conditions.
| Lactoferrin sources as supplements | |
|---|---|
| Product | References |
| Bovine and human milk | Morinaga Industries in Japan (183) DoMO Food Ingredients, a subsidiary of Friesland Dairy Foods, in the Netherlands (184) |
| Human recombinant lactoferrin | Talactoferrin from Agennix, Inc., Houston, Texas, USA (184) |
| Lactoferrin expression in transgenic rice | Ventrus Biosciences, New York City, New York, USA (184) |
| Transgenic cattle expressing human lactoferrin | (185, 186) |
| Transgenic maize | Meristem therapeutics, Clermont-Ferrand, France (184) |
| Lactoferrin supplementation in treatment of various diseases | |
| Might be useful in treating sepsis or necrotizing enterocolitis in preterm neonates | (184) |
| Support for vaginal health | (187) |
| LF may play a protective role in host defense against SARS-CoV infection through binding to HSPGs and blocking the preliminary interaction between SARS-CoV and host cells (cell culture study) | (99) |
| LF is a modulator of innate immune responses in the urinary tract and has potential application in novel therapeutic design for urinary tract infection (animal study) | (188) |
| Possible therapy against Candida albicans in the oral cavity (a hypothesis) | (189) |
| Protection against Chlamydia trachomatis (cell culture study) | (190) |
| Treatment of taste and smell abnormalities after chemotherapy | (52) |
| LF supplements and food with high levels of LF for oral health | (99, 191) |
| LF treatment of black stain associated with of iron metabolism disorders with lactoferrin | (192) |
| Aerosolized bovine LF counteracts infection, inflammation and iron dysbalance in a cystic fibrosis mouse model of Pseudomonas aeruginosa chronic lung infection | (193) |
| LF inhalations for lung health | (194) |
| LF for optimal skin moisture | (195) |