Figure 4.

Estimated glomerular filtration rate (eGFR) (full analysis set [FAS]) in (a) cohort G3 and (b) cohort G4; urinary albumin/creatinine ratio (ACR) (FAS) in (c) cohort G3 and (d) cohort G4; and baseline-adjusted ACR/eGFR in (e) cohort G3 and (f) cohort G4. Data are mean (95% confidence interval). P value is based on non−multiplicity-adjusted P value by t test and post hoc analyses. P value indicates the difference between the treatment groups at 16 weeks using the mixed-effects model with repeated measures with treatment and time as factors, treatment-by-visit interaction, and relevant baseline value as covariate.