TABLE 3.

Top 20 significantly down-regulated circRNAs.

circRNA	P-value	FDR	FC (abs)	Regulation	source	chrom	strand	type	GeneSymbol
hsa_circRNA_405324	0.013412911	0.541205763	4.3231649	down	25070500	chr15	+	sense overlapping	STARD9
hsa_circRNA_405443	0.028911656	0.541205763	3.3381633	down	25070500	chr16	+	intronic	NDE1
hsa_circRNA_406309	0.01797211	0.541205763	3.1653952	down	25070500	chr3	+	intronic	CMSS1
hsa_circRNA_100075	0.029545308	0.541205763	3.1382274	down	circBase	chr1	−	exonic	EMC1
hsa_circRNA_406821	0.020949363	0.541205763	3.0380172	down	25070500	chr6	+	exonic	ARMC2
hsa_circRNA_000361	0.027240076	0.541205763	3.0118108	down	circBase	chr3	−	antisense	PLCL2
hsa_circRNA_082335	0.035559522	0.541205763	3.008493	down	circBase	chr7	+	exonic	KLHDC10
hsa_circRNA_102207	0.013654637	0.541205763	3.0013356	down	circBase	chr17	+	exonic	AFMID
hsa_circRNA_405825	0.015220854	0.541205763	2.522762	down	25070500	chr2	+	exonic	KLF11
hsa_circRNA_074660	0.017052344	0.541205763	2.4763773	down	circBase	chr5	−	exonic	ATOX1
hsa_circRNA_104924	0.01941688	0.541205763	2.4549169	down	circBase	chr9	+	exonic	MVB12B
hsa_circRNA_056037	0.027008503	0.541205763	2.4478589	down	circBase	chr2	−	exonic	BUB1
hsa_circRNA_406780	0.028354789	0.541205763	2.3707217	down	25070500	chr6	−	sense overlapping	DNPH1
hsa_circRNA_024371	0.025742814	0.541205763	2.36132	down	circBase	chr11	+	exonic	PAFAH1B2
hsa_circRNA_061284	0.026417014	0.541205763	2.30245	down	circBase	chr21	+	exonic	USP25
hsa_circRNA_100456	0.009103973	0.541205763	2.2394652	down	circBase	chr1	+	exonic	KCNK2
hsa_circRNA_083919	0.037676327	0.541205763	2.213904	down	circBase	chr8	+	exonic	UNC5D
hsa_circRNA_406295	0.017374416	0.541205763	2.2027287	down	25070500	chr3	+	sense overlapping	SUCLG2-AS1
hsa_circRNA_035426	0.040284453	0.541205763	2.2016635	down	circBase	chr15	+	exonic	TCF12
hsa_circRNA_405296	0.023543643	0.541205763	2.1972163	down	25070500	chr15	+	sense overlapping	TUBGCP5