Table 4. Antibacterial effect of marbofloxacin administered alone and in combination with methyl gallate after oral administration.
| Parameter | MAR | MGM |
|---|---|---|
| Imax | 10.86±0.58 | 10.66±1.14 |
| IC50 | 405.99±11.78 | 584.75±30.06** |
| E0 | 4.05±0.29 | 3.6±0.67 |
| Gamma | 5.41±1.46 | 10±5.51 |
Imax: maximum inhibitory response (difference in the log of number of bacteria (CFU/mL) in the control sample); IC50: Concentration at which 50% of maximum inhibition; E0: the difference in the log number of bacteria in the sample treated with MAR between 0 and 24; Gamma: Exponent for sigmoid Imax model. MAR: marbofloxacin and MGM: Combination of marbofloxacin and methyl gallate. n = 6.
* indicates significance difference (P<0.05).