Table 5. Compliance and outcome of cases of possible serious bacterial infection who treated with simplified treatment and who accepted referral and were treated at district hospital.
Parameters | All PSBI cases | Fast Breathing 7–59 days | Fast Breathing 0–6 days | Clinical Severe Infection 0–59 days | Critical Illness 0–59 days |
---|---|---|---|---|---|
A. Compliance of treatment | N = 959 n/m (%) | N = 147 n/m (%) | N = 34 n/m (%) | N = 685 n/m (%) | N = 93 n/m (%) |
Number of oral amoxicillin doses 14 Doses |
517/959 (53.9) | 105/147 (71.4) | 31/34 (91.2) | 333/685 (48.6) | 48/93 (51.6) |
10–13 Doses | 293/959 (30.6) | 41/147 (27.9) | 3/34 (8.8) | 228/685 (33.3) | 21/93 (22.6) |
6–9 Doses | 10/959 (1.0) | 1/147 (0.7) | - | 9/685 (1.3) | - |
5 or less Doses | 17/959 (1.8) | - | - | 9/685 (1.3) | 8/93 (8.6) |
Other oral antibiotics received§ | 122/959 (12.7) | - | - | 106/685 (15.5) | 16/93 (17.2) |
Injection gentamicin received¶ | N = 812 n/m (%) | NA | N = 34 n/m (%) | N = 685 n/m (%) | N = 93 n/m (%) |
7 injections | 132/812 (16.3) | NA | 16/34 (47.1) | 80/685 (11.7) | 36/93 (38.7) |
5–6 injections | 217/812 (26.7) | NA | 10/34 (29.4) | 192/685 (28.0) | 15/9 (16.1) |
3–4 injections | 90/812 (11.1) | NA | 5/34 (14.7) | 80/685 (11.7) | 5/93 (5.4) |
1–2 injections | 73/812 (9.0) | NA | - | 52/685 (7.6) | 21/93 (22.6) |
Other injectable antibiotic (amikacin) received∞ | 300/812 (36.9) | NA | 3/34 (8.8) | 281/685 (41.0) | 16/93 (17.2) |
B. Outcome for those who accepted simplified treatment (based on respondent’s perception) | N = 959 n/m (%) | N = 147 n/m (%) | N = 34 n/m (%) | N = 685 n/m (%) | N = 93 n/m (%) |
Infants declared as ‘Treatment success’ | 886/959 (92.4) | 140/147 (95.2) | 34/34 (100) | 645/685 (94.2) | 67/93 (72.0) |
Infants declared as ‘Treatment failure’ | 73/959 (7.6) | 7/147 (4.8) | 0/34 (0) | 40/685 (5.8) | 26/93 (28.0) |
Reason for treatment failure | N = 73 n/m (%) | N = 7 n/m (%) | N = 0 n/m (%) | N = 40 n/m (%) | N = 26 n/m (%) |
Left treatment | 45/73 (62.5) | 7/7 (100) | 0/0 (0) | 30/40 (75) | 8/26 (30.8) |
Persistence of presenting sign on day 8 | 1/73 (1.4) | 0/7 (0) | 0/0 (0) | 0/40 (0) | 1/26 (3.8) |
Deaths | 25/73 (34.2) | 0/7 (0) | 0/0 (0) | 09/40 (22.5) | 16/26 (61.5) |
Outcome unknown | 2/73 (2.8) | 0/7 (0) | 0/0 (0) | 01/40 (2.6) | 1/26 (3.8) |
C. Outcome of the illness on Day 7 of those who accepted referral and were treated at district hospital | N = 88 n/m (%) | N = 1 n/m (%) | N = 1 n/m (%) | N = 50 n/m (%) | N = 36 n/m (%) |
Cured | 67/88 (76.1) | 1/1 (100) | 1/1 (100) | 45/50 (90) | 20/36 (55.6) |
Better | 7/88 (8.0) | 0/1 (0) | 0/1 (0) | 02/50 (4) | 05/36 (13.9) |
Still sick | 2/88 (2.3) | 0/1 (0) | 0/1 (0) | 0/50 (0) | 02/36 (5.6) |
Same | 1/8 (1.1) | 0/1 (0) | 0/1 (0) | 0/50 (0) | 01/36 (2.8) |
Outcome unknown | 0/88 (0) | 0/1 (0) | 0/1 (0) | 03/50 (6) | 0/36 (0) |
Deaths | 11/88 (12.5) | 0/1 (0) | 0/1 (0) | 03/50 (6) | 08/36 (22) |
¶ Excluding cases of fast breathing in ages 7–59 days.
§ Oral amoxicillin was unavailable
∞ Injection gentamicin was unavailable