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(a) A reported complex model of p53 peptide and MDM2 N-terminal domain (PDB ID- 1YCR). (b) A reported complex model of p53 peptide and MDMX N-terminal domain (PDB ID- 3DAC). (c) A complex model of S100A1 and MDM2 N-terminal domain generated via the HADDOCK program. (d) Overlapping of the complex models indicated in a, b, and c showed possible interference of S100A1 between p53 peptide and MDM2/MDMX N-terminal domain.
