Table 2. Summary of model results for phenotypes shown in Figs 1 and 2.

The subscript in $h_{\left(l\right)}^2$ indicates that for the qualitative phenotypes (the first eight) the reported SNP heritability is on the liability scale. MDD: Major Depressive Disorder; CAD: coronary artery disease; AD: Alzheimer’s Disease (excluding APOE locus; *for the full autosomal reference panel, i.e., including APOE, $h_l^2=0.15$ for AD—see S1 Appendix (p. S17)); BMI: body mass index; ^†ALS: amyotrophic lateral sclerosis, restricted to chromosome 9; LDL: low-density lipoproteins; HDL: high-density lipoproteins. ^$In addition to the 2014 height GWAS (N = 251,747 [46]), we include here model results for the 2010 (N = 133,735 [69]) and 2018 (N = 707,868 [49]) height GWAS; there is remarkable consistency for the 2010 and 2014 GWAS despite very large differences in the sample sizes—see S1 Appendix (p. S17). Confidence intervals are in S1 Appendix (p. S12).

Phenotype	π1	${\sigma }_{\beta }^2$	${\sigma }_0^2$	ncausal	$h_{\left(l\right)}^2$
MDD	4.01E-3	7.20E-6	1.06	4.4E4	0.07
Bipolar Disorder	2.70E-3	5.25E-5	1.05	3.0E4	0.16
Schizophrenia	2.84E-3	5.51E-5	1.14	3.1E4	0.21
CAD	1.14E-4	1.47E-4	0.97	1.3E3	0.03
Ulcerative Colitis	1.26E-4	8.82E-4	1.14	1.4E3	0.11
Crohn’s Disease	9.56E-5	1.70E-3	1.17	1.1E3	0.18
AD (no APOE)*	1.11E-4	2.22E-4	1.05	1.2E3	0.08
ALS†	1.43E-5	3.04E-3	1.02	7	0.00
Education	3.20E-3	1.57E-5	1.00	3.5E4	0.12
Intelligence	2.20E-3	2.32E-5	1.28	2.4E4	0.13
BMI	6.44E-4	4.28E-5	0.88	7.5E3	0.07
Height (2010)$	4.32E-4	1.66E-4	0.94	4.8E3	0.17
Height (2014)	5.66E-4	1.23E-4	1.66	6.2E3	0.17
Height (2018)$	8.56E-4	9.46E-5	2.50	9.4E3	0.19
Putamen Volume	4.94E-5	9.72E-4	1.00	540	0.11
LDL	3.58E-5	6.61E-4	0.96	390	0.06
HDL	2.37E-5	1.25E-3	0.97	260	0.07
TC	4.26E-5	8.99E-4	0.96	469	0.09