Date	Event	Description
7 May 2020	New citation required but conclusions have not changed	Despite the inclusion of results from a further study (n = 38) in the review, our conclusions remain the same.
7 May 2020	New search has been performed	A search of the Cystic Fibrosis and Genetic Disorders Group's Cystic Fibrosis Trials Register identified two new references potentially eligible for inclusion in the review which were found to be trial registry entries for a study already listed as ongoing and which has now been included (Kuitert 2010). A summary of findings table has been included at this update.
20 June 2017	New search has been performed	A search of the Cochrane Cystic Fibrosis and Genetic Disorders Review Group's Cystic Fibrosis Trials Register did not identify any new references potentially eligible for inclusion in this review.
20 June 2017	New citation required but conclusions have not changed	A former co‐author, Prof Zbys Fedorowicz, has stepped down from the review and been replaced by Dr Amy Price. No new studies have been included in this updated review, therefore our conclusions remain the same.
13 April 2015	Amended	Contact details updated.
4 February 2015	Amended	Source of support for author VT clarified and added.
18 December 2014	New citation required but conclusions have not changed	We have not been able to include any new information, hence our conclusions remain the same.
18 December 2014	New search has been performed	A search of the Cystic Fibrosis and Genetic Disorders Group's Cystic Fibrosis Trials Register did not identify any potentially eligible references for this review.
21 January 2013	New citation required but conclusions have not changed	No new information has been added to the review, therefore the conclusions have not changed.
21 January 2013	New search has been performed	A search of the Group's Cystic Fibrosis Register identified a single new reference to an ongoing study already listed in the review (Kuitert 2010a).
22 May 2012	Amended	Contact details updated.