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. Author manuscript; available in PMC: 2021 Jun 15.
Published in final edited form as: Vaccine. 2020 May 6;38(29):4601–4608. doi: 10.1016/j.vaccine.2020.05.009

Figure 4.

Figure 4.

Adjuvants enhance development of T follicular helper cells (A) and germinal center B cells (B) after vaccination. One or two way ANOVA with multiple comparisons was used to compare adjuvanted groups to vaccination with eVLP alone (* = p<0.05, ** = p<0.005, *** = p<0.0005, **** = p<0.0001). Protection after adoptive transfer of sera from vaccinated animals. 500ul or 200ul of immune sera from Advax-2 or -4 or pICLC immunized animals was transferred to naïve C57BL/6 mice 24 hours prior to challenge with ma-EBOV; p-value based on Log-rank Mantel-Cox test (C).