Table 2.

Comparison of structural and functional parameters of optic nerve head between preperimetric primary open-angle glaucoma patients according to presence of parapapillary deep-layer microvasculature dropout

Variables	Eyes with MvD_P (33 eyes, 33 patients)	Eyes without MvD_P (61 eyes, 61 patients)	P−value
Visual field parameters (dB)
Mean deviation	−1.52 ± 1.67	−0.53 ± 1.26	0.002*
Pattern standard deviation	1.84 ± 0.65	1.65 ± 0.41	<0.001‡
Superior retinal sensitivity	27.88±2.27	29.04±1.94	0.020‡
Inferior retinal sensitivity	28.78±2.12	30.37±2.15	0.002‡
Superior total deviation sensitivity	−1.56±2.03	−0.57±1.59	0.010*
Inferior total deviation sensitivity	−1.89±1.80	−0.61±1.45	<0.001*
Circumpapillary RNFL thickness (μm)
Global area	80.1 ± 10.7	90.6 ± 9.7	<0.001*
Temporal	63.4 ± 12.2	72.4 ± 12.0	0.001*
Nasal	65.5 ± 12.7	71.5 ± 13.4	0.038*
Superotemporal	106.6 ± 23.9	117.2 ± 23.7	0.043*
Superonasal	98.7 ± 24.2	111.7 ± 23.9	0.014*
Inferonasal	92.7 ± 21.5	100.3 ± 19.5	0.085*
Inferotemporal	99.5 ± 24.0	125.7 ± 25.1	<0.001*
Focal lamina cribrosa defect, n (%)	19 (57.6 %)	13 (21.3 %)	<0.001†
Disc Hemorrhage, n (%)	4 (12.1 %)	3 (4.9 %)	0.207†
JPCT (μm)	122.9 ± 37.6	127.2 ± 28.1	0.531*
BMO area (mm2)	2.66 ± 0.80	2.60 ± 0.72	0.893‡
βPPA+BM width (μm)	199.7 ± 105.5	164.5 ± 76.6	0.066*
βPPA−BM width (μm)	240.9 ± 306.7	128.0 ± 186.1	0.029*

Values are shown in mean ± standard deviation.

Statistically significant values are shown in bold.

^*The comparison was performed by using independent samples t-test.

^†The comparison was performed by using Chi-squared test.

^‡The comparison was performed by using Mann-Whitney test.

RNFL = retinal nerve fiber layer; JPCT = Juxtapapillary choroidal thickness; BMO = Bruch’s membrane opening; βPPA_+BM = ß-zone parapapillary atrophy with Bruch’s membrane; PPA_−BM = ß-zone parapapillary atrophy without Bruch’s membrane.