Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 10;22(6):1079–1087. doi: 10.1038/s41436-020-0759-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. If you remix, transform, or build upon this article or a part thereof, you must distribute your contributions under the same license as the original. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/.

PMC Copyright notice

Fig. 5 — The gCNV algorithm provides four quality metrics for every predicted CNV: QA, QS, QSE, and QSS. QA is the complementary Phred-scaled probability that all points (i.e., targets or bins) in the segment agree with the segment copy-number call. QS is the complementary Phred-scaled probability that at least one point (i.e., target or bin) in the segment agrees with the segment copy-number call. QSE is the complementary Phred-scaled probability that the segment end position is a genuine copy-number changepoint. QSS is the complementary Phred-scaled probability that the segment start position is a genuine copy-number changepoint. Violin plots show the relative probability density of the distribution of each quality metric, while internal box plots show the 25th, median, and 75th percentile of distribution. The red and black data points represent CNVs within the distribution that were experimentally determined to be either true positives (black) or false positives (red) by quantitative polymerase chain reaction (qPCR) validation.