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Prss56 knockout mice develop elevated IOP. (A) IOP is significantly higher in Prss56−/− mice compared to control Prss56+/− mice at 3 and 5 months (mo). n=50 and n=48 for Prss56+/− eyes at 3 and 5 months, respectively; n=38 Prss56−/− eyes at each age examined. Data are mean±s.d., ***P<0.001, Student's t-test. (B) Histogram showing the proportion of eyes in each IOP range at 3 and 5 months.
