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. 2020 Jun 4;10:9110. doi: 10.1038/s41598-020-66058-x

Table 1.

Demographic and clinical characteristics.

Control group
(n = 27)
Postpartum group
(n = 24)
P value
Demographic characteristics
Age (y) 29.4 ± 4.3 31.0 ± 3.0 0.111
Duration of education (y) 16.0 (16.0–19.0) 16.0 (16.0–19.0) 0.279
Married 6 (22.2%) 24 (100%)
Normal delivery/C-sec N/A 17/7 N/A
Number of children N/A 1 (1.0 – 2.0)
Breast feeding N/A 14 (58.33%) N/A
Interval between MRI scan and delivery date (d) N/A 103.3 ± 16.4 N/A
Self-report questionnaires
Number of awakenings 0.0 (0.0–0.0) 1.75 (0.3–2.0) <0.001
Total sleep time per day (h) 6.0 (6.0–7.0) 7.0 (6.0–8.5) 0.099
Lack of sleep 5.0 (2.0–7.0) 4.5 (3.0–6.0) 0.863
EPDS 5.0 (3.8–8.0) 5.5 (2.0 – 11.25) 0.882
BDI 5.0 (3.0–8.0) 8 (5. 5 – 10.0) 0.043
CFQ 26.8 ± 9.5 35.5 ± 12.8 0.008
Estradiol assay (pg/mL) 89 (52.0–201.0) 40.5 (25.0–66.5) 0.007
Neuropsychological test
COWAT (Animal) 29.0 ± 4.5 20.1 ± 5.5 0.550
15-item K-BNT 14.0 (14.0–15.0) 14.0 (14.0–15.0) 0.621
Digit span forward 15.0 (14.0–16.0) 14.0 (13.0–15.0) 0.073
Digit span backward 13.0 (11.0–14.0) 12.5 (9.0–14.0) 0.321
Digit span sequencing 9.4 ± 2.1 8.0 ± 2.5 0.031*
Word List Memory 26.0 (24.0–27.5) 26.0 (24.0–27.0) 0.563
Word List Recall 90.0 (86.8–100.0) 100.0 (90.0–100.0) 0.068
Word List Recognition 10.0 (10.0–10.0) 10.0 (10.0–10.0) 0.342
TMT_A 20.5 (19.0–25.0) 20.5 (18.0–28.0) 0.778
TMT_B 51.5 (42.8–80.8) 51.0 (38.5–61.0) 0.260

Normally distributed data are expressed as means ± standard deviations; otherwise, data are expressed as medians with the interquartile range in parentheses. Abbreviations: BDI, Beck Depression Inventory; CFQ, Cognitive Failure Questionnaire; COWAT, Controlled Oral Word Association test; EPDS, Edinburgh Postnatal Depression Scale; 15-item K-BNT, 15-item Korean version of the modified Boston Naming Test; and TMT, Trail Making Test.