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. 2020 Jun 4;11:2816. doi: 10.1038/s41467-020-16703-w

Fig. 2. Crystal structure of ThsA.

Fig. 2

a A two-domain architecture of ThsA consisting of an N-terminal sirtuin-like domain (blue) and a C-terminal SLOG-like domain (cyan). b Structure of the N-terminal sirtuin-like domain in ThsA. c Structural alignment of the Rossmann-like fold portion of the ThsA N-terminal domain (blue) with a sirtuin protein, Thermotoga maritima CobB (PDB ID: 2H2G; gray). d Structure of the C-terminal SLOG-like domain of ThsA. e Common features of the SLOG superfamily shared by the C-terminal domain of ThsA. ThsA residues conserved in the STALD family within the SLOG superfamily are shown in stick representation. Secondary structural elements of ThsA common to the SLOG superfamily are also indicated.