Fig. 1.

Schematic stages of adipogenesis in relation to ECM protein expression. Key steps of adipogenesis are indicated. Relative ECM protein expression is shown as curves. Fibronectin and fibrillin-1 (green curve) is present in the early commitment phase and decreases during adipocyte differentiation, whereas collagen I, III, V, VI and laminin (red curve) appear during mid-differentiation and increase further until maturation. Basement membrane components, including collagen IV and heparan sulfate proteoglycans (orange curve) are mainly present when adipocytes are differentiated