Table 1.
Tissue | Principle Function of Asprosin | References |
---|---|---|
Adipose Tissue | Main source of asprosin production and secretion | Romere et al. 2016 |
Liver | Primary target tissue; promotes hepatic glucose production |
Romere et al. 2016 Ko et al. 2019 |
Receptor binding (OLFR734) | Li et al. 2019 | |
Pancreas | Reduces insulin secretion; amplifies inflammatory response and apoptosis of pancreatic cells | Lee et al. 2019 |
Brain | Increases appetite and food intake | Duerrschmid et al. 2017 |
Skeletal Muscle | Augments endoplasmic reticulum stress and inflammation | Jung et al. 2019 |