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. 2020 Apr 12;14(2):159–173. doi: 10.1007/s12079-020-00566-3

Table 1.

Summary of the principle roles of asprosin in different metabolic tissues and organs

Tissue Principle Function of Asprosin References
Adipose Tissue Main source of asprosin production and secretion Romere et al. 2016
Liver Primary target tissue; promotes hepatic glucose production

Romere et al. 2016

Ko et al. 2019

Receptor binding (OLFR734) Li et al. 2019
Pancreas Reduces insulin secretion; amplifies inflammatory response and apoptosis of pancreatic cells Lee et al. 2019
Brain Increases appetite and food intake Duerrschmid et al. 2017
Skeletal Muscle Augments endoplasmic reticulum stress and inflammation Jung et al. 2019