Table 2.

Differential metabolites between periodontitis and healthy controls

Peak	Mean P	Mean N	VIP	P value	Q value	Fold change	Log_foldchange
Glycine-d5	0.051333284	0.002518903	2.686654583	1.49E-07	3.65352E-06	20.37922203	4.349027073
N-Carbamylglutamate 2	0.001037846	0.000105564	2.630242979	4.21401E-09	2.5869E-07	9.831450847	3.297404334
Fructose 1	0.002357247	0.000398217	2.398089278	0.001428095	0.017702445	5.919500674	2.565475486
2-Butyne-1,4-diol	0.006857957	0.001194529	2.879871275	7.8385E-09	3.84952E-07	5.741140703	2.521337413
5-Dihydrocortisol 3	0.000558885	9.8688E-05	1.227185617	0.002842353	0.027874389	5.663150523	2.501604876
N-Acetyl-beta-D-mannosamine 1	0.000319463	6.02506E-05	2.178661077	0.001755285	0.020494345	5.302237027	2.406601165
4-Hydroxyphenylacetic acid	0.002672063	0.000709054	1.96772351	0.003112315	0.029393691	3.768488233	1.913985888
Citramalic acid	0.002650632	0.000758167	2.984629212	9.68575E-08	2.91543E-06	3.49610666	1.8057492
Uracil	0.007927636	0.003428043	1.617699878	0.000549653	0.008165377	2.312583439	1.20950542
beta-Glutamic acid 1	0.002995735	0.002020754	1.293178024	0.020879645	0.099659996	1.48248402	0.568016553
Monoolein	0.007769257	0.005862759	1.627516713	0.02848719	0.117778288	1.325187884	0.406196919
Methylmalonic acid	0.029476006	0.033940995	1.664596792	0.018708654	0.094957487	0.868448476	−0.203487837
Thymidine 3	0.001377672	0.001740672	1.096219131	0.009559978	0.066454136	0.791459902	−0.337411835
Octadecanol	0.001733205	0.002235684	1.739203072	0.03129264	0.123639982	0.775245838	−0.367274219
1-Monopalmitin	0.000614955	0.000854443	1.157584723	0.008945999	0.063789651	0.719715264	−0.474501838
O-Phosphoserine 1	0.00071198	0.001001571	1.001597189	0.010134474	0.068828752	0.710863854	−0.492354816
Lactamide 2	0.000382039	0.000585076	1.755482094	0.009031916	0.064170744	0.652973669	−0.614903278