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Clinical staging verification for driver transition points in patients with the same CMS.
| Stage 1 | Stage 2 | Stage 3 | Stage 4 | |
| CMS1 | SPERT/AR | EP300 | ||
| CMS2 | COL6A3 | AR | ||
| CMS2 | LRP1B/FAT4/ANK2 | MAP1B/NFASC/LRP2/SCN3A/LPA | ||
| CMS2 | LRP2 | AR | ||
| CMS3 | PCLO/CREBBP | CACNA1S/EGFR | ||
| CMS4 | CTNNB1 | SMAD4 | ||
| CMS4 | CTNNB1 | PTEN/NFASC/RUNX1T1 |
