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. 2020 May 29;10:250. doi: 10.3389/fcimb.2020.00250

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Copyright © 2020 Wang, Zhou, Tang, Yu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DNA methylation and expression of (A) S100A9, (B) SGO1, and (C) ESPL1 in ETEC F4ab infected cells. These genes were all up-regulated (left panel) and hypomethylated (right panel) compared to uninfected controls. Panels 1-3 and 4-6 indicate the differentially methylated peaks in control and F4ab infected cells by MeDIP-chip (SignalMap software, NimbleGen). P < 0.01 and P < 0.05 indicate highly significant difference and significant difference between uninfected and F4ab infected cells, respectively.