TABLE 2.
miRNA | Target(s) | Role and function in SMC dynamics | References |
miRNA-214 | NCK associated protein 1 (NCKAP1) | Migration, Proliferation, and Neointima Hyperplasia | Afzal et al., 2016 |
miRNA-130a | MEOX1 | Proliferation, migration | Wu et al., 2011 |
miRNA-675 | PTEN | Proliferation | Lv et al., 2018 |
miR-221/-222 | CDKN1B, CDKN1C | Proliferation, migration, and anti-apoptotic effects | Davis et al., 2009; Liu et al., 2009 |
miRNA-22-3p | High mobility group box-1 (HMGB1) | Proliferation and Migration and Neointimal Hyperplasia | Huang et al., 2017 |
miRNA-23b | The transcription factor forkhead box O4 (FoxO4) | Phenotypic switching | Iaconetti et al., 2015 |
miRNA-195 | The Cdc42, cyclin D1, and fibroblast growth factor 1 (FGF1) genes | Regulate cell phenotype and prevents neointimal formation. | Wang et al., 2012 |
miR-206 | ARF6, SLC8A1 | Differentiation | Lin et al., 2016 |
miRNA-34a | Neurogenic locus notch homolog protein-1 (Notch1) | Proliferation and migration | Chen et al., 2015 |
miR-146a | KLF4/5 | Differentiation, proliferation | Sun et al., 2011 |