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. 2020 May 29;11:530. doi: 10.3389/fgene.2020.00530

TABLE 2.

Detailed list of the VSMC-associated miRNAs.

miRNA Target(s) Role and function in SMC dynamics References
miRNA-214 NCK associated protein 1 (NCKAP1) Migration, Proliferation, and Neointima Hyperplasia Afzal et al., 2016
miRNA-130a MEOX1 Proliferation, migration Wu et al., 2011
miRNA-675 PTEN Proliferation Lv et al., 2018
miR-221/-222 CDKN1B, CDKN1C Proliferation, migration, and anti-apoptotic effects Davis et al., 2009; Liu et al., 2009
miRNA-22-3p High mobility group box-1 (HMGB1) Proliferation and Migration and Neointimal Hyperplasia Huang et al., 2017
miRNA-23b The transcription factor forkhead box O4 (FoxO4) Phenotypic switching Iaconetti et al., 2015
miRNA-195 The Cdc42, cyclin D1, and fibroblast growth factor 1 (FGF1) genes Regulate cell phenotype and prevents neointimal formation. Wang et al., 2012
miR-206 ARF6, SLC8A1 Differentiation Lin et al., 2016
miRNA-34a Neurogenic locus notch homolog protein-1 (Notch1) Proliferation and migration Chen et al., 2015
miR-146a KLF4/5 Differentiation, proliferation Sun et al., 2011