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. 2020 May 29;11:804. doi: 10.3389/fphar.2020.00804

Table 1.

Effects sizes and efficacy per treatment and variable.

Effects sizes1 Fold changes relative to FLX2
Variables/treatments FLX PE EE PE EE
Body weight 0% 8% 45% 8.0 45.0
Locomotion 2% 15% 44% 7.5 22.0
Sucrose intake 25% 58% 63% 2.3 2.5
Sucrose preference 0% 20% 50% 20.0 50.0
Immobility 50% 24% 40% 0.5 0.8
Swimming 41% 33% 40% 0.8 1.0
5-HT 69% 0% 49% 0.7
5-HIAA 25% 0% 35% 1.4
5-HT turnover 39% 0% 46% 1.2

1Effect sizes corresponded to eta-squared coefficients expressed as percentages, which derived from planned comparisons between each treatment and SI. The grey-shaded numbers indicate the coefficients that were not significant. 2Fold changes were estimated with the eta-squared coefficients of PE and EE in comparison to those of FLX.