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. 2020 May 29;11:809. doi: 10.3389/fphar.2020.00809

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Copyright © 2020 Cheng, Shou, Lang, Jin, Liu, Tang, Yang and Fu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inflammatory factors and chemokines in the microenvironment of hepatocellular carcinoma are down-regulated by GHJCD. (A) IL-6 content in liver tissue. (B) IL-10 content in liver tissue. (C) Expression of TNF-α in the liver. (D) CCl-2 content in liver tissue. IL-6, IL-10, TNF-α, and CCl-2 data in the liver cancer microenvironment were analyzed by ANOVA. The homogeneity test was first performed, P > 0.05, the variances were uniform, and the LSD (L) test was used for multiple comparisons afterward, P < 0.05, the variances were not uniform.*p < 0.05 vs. control; ^#p < 0.05, ^##p < 0.01 vs. model. Data were analyzed using single-variance t-test.