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. 2020 May 29;8:361. doi: 10.3389/fcell.2020.00361

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Copyright © 2020 Ren, Song, Ni, Kang and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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20-hydroxyecdysone (20E) regulation of the cell cycle progression. In Drosophila melanogaster, 20E-EcR positively regulates Tramtrack (Ttk) to transit the endocycle to mitotic cycle. In Bombyx mori, 20E promotes cell cycle progression through activation of c-Myc. In Plodia interpunctella, 20E induces an arrest of cells in G2 phase by decreasing the expressions of cyclin (Cyc) A and B. In Aedes albopictus, 20E application results in an accumulation of cells in G1 phase by decreasing CycA and increasing Dacapo (DAP) expresisons. EcR, ecdysone receptor.